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Gallbladder problems right upper abdominal pain, particularly after eating fatty foods Severe allergic reactions rash, swelling of face or throat, difficulty breathing Diabetic retinopathy complications sudden vision changes (in patients with pre-existing retinopathy) Acute kidney injury particularly in the context of severe dehydration The MHRA advises that patients should be counselled about these risks before starting treatment

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That decline correlates with reduced wound healing speed, collagen production, and tissue repair capacity

Tumor Growth Potential: Medical summaries indicate that enhanced blood supply from angiogenesis may support tumor growth, and the potential risk has not been evaluated in clinical studies